Effect of administration of isatin on alkaline phosphatase of various organs of rat.

نویسندگان

  • B Singh
  • P Kumar
  • J P Nagpaul
  • R Sharma
  • R C Bansal
چکیده

In vivo administration of isatin (200 mg/kg) significantly lowered the activity of rat kidney alkaline phosphatase after 5 hr but enhanced the activity of rat duodenal and jejunal enzyme after 2 and 5 hr (P less than 0.01). The increased activity of the duodenal and jejunal alkaline phosphatase might be due to the induction of the enzyme by isatin.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In vivo study for evaluation the effect of Aluminum exposure on rat livers

The aim of the current research was to investigate the effect of aluminum exposure on humoral immunity (immunoglobulin G and immunoglobulin M serum levels), function enzymes, and histological alterations in the liver of rats. Materials & Methods: Sixteen albino male rats at fifteen weeks were grouped into four groups, and administered with aluminum chloride at 35g/Kg of body weight for 8, 12 ...

متن کامل

P-44: Oral Gibberellic Acid Administration Impact on Testicular Histochemistry

Background: Gibberellic acid (GBA) is a naturally occurring and commercially produced plant growth regulator which may cause a variety of effects including the stimulation of seed germination in some cases. Histochemical changes in testicular tissue including carbohydrates, lipids and alkaline phosphatase enzyme changes were evaluated. Materials and Methods: Twenty seven mature male rats after ...

متن کامل

The effects of chromium and cadmium on the activity of alkaline phosphatase lsoenzmes in rats

The aim of this study was to Investigate the toxic effects of chromium and cadmium on the activity of two isoenzymes of alkaline phosphatase in vitro and in vivo experiments. Oral administration and peritoneal injection of  CdCl2 or CrCl3 in rats reduced serum alkaline phosphatase by 21.5℅ and 25.5℅ respectively. At the same time high molecular weight alkaline phosphatase was elevated by 138℅ a...

متن کامل

The Effect of Eight Weeks of Aerobic Exercise and Vitamin-D Supplementation on Osteocalcine and Alkaline Pphosphatase in Rats Poisoned with H2O2

Background and Objectives: Osteoporosis is one of the bone diseases that various factors such as oxidative stress have a role in creating it. The current research aimed to examine the synchronous effect of aerobic physical exercise and Vitamin D supplementation on osteocalcine and alkaline phosphatase in rats poisoned by H2O2.  Materials & Methods: Sixty adult male Wistar rats were randomly di...

متن کامل

Protective Effect of Methanolic Leaf Extract of Caesalpinia Bonduc (L.) on Gentamicin-Induced Hepatotoxicity and Nephrotoxicity in Rats

The present study was conducted to evaluate the protective effect of methanolic leaf extract of Caesalpinia bonduc (L.) on gentamicin-induced hepatotoxicity and nephrotoxicity in rats . A control group (saline, group I, n = 6) was compared with rats administrated 80 mg/kg gentamicin, once daily for 7 days (groups II, III and IV). The effect of methanolic leaf extract of Caesalpinia ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Indian journal of physiology and pharmacology

دوره 22 3  شماره 

صفحات  -

تاریخ انتشار 1978